"We found that people are likely getting a double whammy of exposure in terms of health during rush-hour commutes," said Michael Bergin, professor of civil and environmental engineering at Duke. "If these chemicals are as bad for people as many researchers believe, then commuters should seriously be rethinking their driving habits."

"There are a lot of reasons an in-car air sample would find higher levels of certain kinds of air pollution," said Heidi Vreeland, a doctoral student in Bergin's lab and first author of the paper. "The chemical composition of exhaust changes very quickly, even in the space of just a few feet. And morning sun heats the roadways, which causes an updraft that brings more #pollution higher into the air."

Oxidative stress -- the phenomenon antioxidant foods are supposed to address -- is thought to play a role in a wide range of diseases including Asperger's syndrome, ADHD, cancer, Parkinson's disease, Alzheimer's disease, atherosclerosis, heart failure and heart attack, sickle cell disease, autism, infection, chronic fatigue syndrome and depression.

"There's still a lot of debate about what types of pollution are cause for the biggest concern and what makes them so dangerous," Bergin said. "But the bottom line is that driving during rush hour is even worse than we thought."

"My two cents is that this is really an urban planning failure," said Greenwald, who is now an assistant professor of environmental health at Georgia State University. "In the case of Atlanta, the poor air quality on the highways is due to the fact that 6 million people live in the metro area, and most of them have little choice but to get into an automobile to go to work or school or the store or wherever. Auto-centric transportation plans do not scale well to cities of this size, and this is one more example of how traffic negatively affects your health."